Microscopy Imaging Center

PhD Defense

Alberto Mattei, student ot the PhD program Cutting Edge Microscopy (CEM), will give his PhD defense on September 1, 2021 at 10.00 am online via Zoom
Title: Exploring Signaling Mechanisms regulating genetic and non-genetic Drug Resistance in Melanoma
Please request access to this online event via e-mail to Rahel Eyer.

"Metastatic melanoma is a very aggressive type of cancer that in over 50% of cases carries a BRAF^V600E mutation. The mutated BRAF drives aberrant MAPK-ERK pathway activation and tumor progression. Selective BRAF^V600E inhibitors have been on the market since 2011, but drug resistance almost invariably develops and patient relapse in the clinic. We explored mechanisms that regulate genetic and non-genetic drug resistance in melanoma."